ABOUT HYPEREMESIS GRAVIDARUM

More than just morning sickness, HG impacts every aspect of a mother’s life, including her health, her well-being and the development of her child.

UNDERSTANDING THE SPECTRUM: WHAT ARE NVP AND HG?

Nausea and Vomiting in Pregnancy (NVP) spans from mild morning sickness to a severe, debilitating condition known as Hyperemesis Gravidarum (HG).

While morning sickness is common and usually resolves by the second trimester, HG involves relentless nausea, vomiting, dehydration, and weight loss that significantly impacts daily life.

A relentless cycle of symptoms, HG profoundly affects every aspect of life, including work, relationships, and family planning.

It is a leading cause of hospitalization in early pregnancy and significantly raises the risks for both
mother and baby.

For up to 10.8% of pregnant women,
HG poses serious risks to both mother and baby.

Symptoms of HG

Persistent vomiting or prolonged nausea

(unable to keep food or liquids down)

Strong aversions to foods and beverages

Significant weight loss

(often >15% of pre-pregnancy weight)

Light-headedness or dizziness

Dehydration

(dry mouth, reduced urination, dark urine)

Severe fatigue or weakness

(inability to perform daily tasks)

Constipation

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IMPACT TO MOTHERS & BABY

Though HG is officially diagnosed in 1-3% of pregnancies, research suggests the condition is far more common, with severe vomiting affecting up to 16% of pregnant women.

The leading cause of hospitalization in early pregnancy, HG is the second most common cause of hospitalization during pregnancy overall, after preterm labor.

Of Mothers with HG

0%
Will Experience
Preterm Birth
0%
Will Consider
Suicide
0%
Will Lose
Their Baby
0%
Will Suffer
Symptoms of PTSD

Children Born to
Mothers with HG are

150%
More Likely to Develop a Neurological Disorder
0%
More Likely to Develop Asthma
0%
Experience Speech / Language Issues
0%
More Likely to Suffer from Autism

As well as including post-partum depression and anxiety, the long-term psychological impact of HG also causes more than three-quarters of families to reconsider plans for future pregnancies, with 35% limiting family size due to fears of HG recurrence.

These physical and emotional consequences of HG, which can require multiple ER visits or inpatient hospitalization make early intervention essential.

HG & ME

CHALLENGES IN DIAGNOSIS
AND TREATMENT

The lack of standardized diagnostic criteria often delays treatment, leaving many patients suffering unnecessarily.

Tools such as the HELP Score exist to assess HG severity but are often
underutilized, resulting in delayed or inconsistent treatment.

HG Costs the U.S. $3 Billion Annually

Emergency room visits, hospitalizations, and lost productivity burden families, providers, and the healthcare system. A comprehensive, early-intervention approach could dramatically reduce these costs.

The Broken Care Model

Most treatment protocols rely on a “wait-and-escalate” model:

Initial approach: Conservative measures like lifestyle changes and anti-nausea medications are suggested first, even in cases of severe symptoms.

Progression: Medical interventions, such as IV fluids or antiemetics, are only introduced after symptoms have significantly worsened.

This approach delays care, often leading to frequent ER visits and hospitalizations.

OUR TREATMENT
About GDF15

Three independent genetic variants of GDF15, a hormone that influences appetite, taste and vomiting, have been linked to the risk of HG.

Genetics

Variations in the GDF15 and PGR genes strongly increase the risk of developing HG.

Hormonal Shifts

Elevated levels of pregnancy hormones, such as hCG, may contribute to the severity of nausea and vomiting.

Additionally, causes may vary between patients depending on biological make-up (genetics), body chemistry, fetal gender, and overall health.

(732) 538-5149
CALL FOR A FREE CONSULTATION

HARMONIA’S COLLABORATIVE CARE MODEL

Based on proven care models, Harmonia’s proactive, early intervention addresses patients’
symptoms as soon as they arise, aiding providers, and improving outcomes for mothers and babies

FOR PRACTICES

  • Reduce calls, appointments and refills
  • Keep patients out of the ER
  • Bill outside of global reimbursements
  • Stay updated on treatment and progress
Discover
Hi Leslie, I’m wondering is it
possible to book an appointment?
Hi Samantha
Yes, You can book through our website

FOR PATIENTS

  • Get a diagnosis
  • Receive reliable, effective treatment in comfort
  • Monitor your pregnancy weight and nutrition
  • Improve the health of you and your baby
GET HELP

Looking for help to manage current NVP or HG symptoms or planning for a future pregnancy?

(732) 538-5149
CALL FOR A FREE CONSULTATION

Discover more about the symptoms and impact of NVP and HG, explore other mother’s experiences, and discover how Harmonia’s research is forging better, more effective care for all women

Research

OUR Research

Understanding Drivers, Barriers & Strategic Needs for HG Treatment Centers: A Summary Comparisons between OBGYNs & NPs/PAs

Conducted by IPSOS/Harmonia Healthcare Abstract: This research was conducted to establish current awareness levels of: Hyperemesis Gravidarum (HG), and Nausea and Vomiting in Pregnancy (NVP); HG treatment centers; treatment options

It’s Not ‘Just’ Morning Sickness

Pregnancy can bring its share of challenges. For many women, pregnancy-related nausea and vomiting, or “morning sickness,” is simply a part of the ride. Around 9 in 10 women experience

A Cure For HG (Hyperemesis Gravidarum) Is Coming

Source: by RAE NUDSON July 10, 2024 Hyperemesis gravidarum, or HG, is a debilitating pregnancy nausea that affects 2% of pregnancies. Researchers know how to cure it — if they

Harmonia Healthcare accepts patients with Medicaid and Cigna insurance plans. For other forms of insurance, we are cash pay but can provide patients with a super bill to submit to insurance.
GET HELP

READY FOR RELIEF?

Our skilled team is here to offer you the compassionate care you deserve. Whether in-clinic or via telehealth, Harmonia Healthcare is dedicated to helping you feel stronger every step of your pregnancy journey.

We work hand-in-hand with your regular healthcare provider to ensure you’re getting the best care possible and keep them updated on the treatments you’re receiving, so they can continue to monitor the overall health of you and your baby.

No Referral Needed

Call or Text for a Complimentary Consultation (732) 538-5149

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